Psychiatric disorders show substantial comorbidity between diagnoses and marked heterogeneity within diagnoses, which contributes to the apparent nonspecificity of neural mechanisms associated with psychopathology. This art depicts mosaic tiles of disparate colors and shapes progressively merging into a highly stylized rendering of functional connectivity map in the brain (from the Human Connectome Project). It highlights the tension between heterogeneity of symptoms and convergence of neural mechanisms underlying psychopathology.